The Science

Learn more about the biology behind your egg count, as well as WHEN’s patented collection kit that delivers you clinical grade results from the comfort of your home.

It only takes one egg

First of all, let’s get this out of the way: fertility is a complex picture with many important things to consider and no single factor can predict your ability to conceive.

Why then is your egg count one of the first things that a fertility specialist will want to understand when assessing your fertility?

Because having an egg available to be released and fertilised is one of the keys to being able to conceive. But if knowing your egg count can’t predict if you’ll be able to become pregnant, what does it tell you?

Your egg count can:

Estimate if you have more or less eggs than what is expected for someone of your age.

Help highlight if you are at risk of running out of eggs earlier than what would be expected

Predict how you might respond to assisted reproductive treatments (like egg freezing or IVF)

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So while your egg count is not a fertility crystal ball, it does give you valuable insight that you can use to make more informed decisions that support your family planning goals – whatever that looks like for you.

But wait, how many eggs do I have?

Starting out

A person with ovaries is born with all the eggs they will ever have (around 1-2 million) and that number decreases as they age.

By the time you hit puberty, around 25% of the eggs remain – although this sounds a little scary, it’s actually completely normal.

As you age

The decline usually continues steadily until the mid 30’s, at which point it generally starts to speed up. By your early 50’s, a person with ovaries will typically reach menopause (which actually means the egg count has reached near zero.)

But here’s the thing...

The rate of egg decline during those reproductive years is different for each individual, so it’s impossible to predict your egg count at any point without actually testing for it. 

And that’s where Anti-Mullerian Hormone (AMH) comes in.

AMH:
A conversation
between follicles

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Anti-Müllerian Hormone

When we want to estimate egg count, it's impossible to actually count the number of eggs because they're too small. But we know that the eggs grow inside of follicles in the ovaries and each follicle produces a hormone called Anti-Mullerian Hormone (AMH). AMH is used by the follicles to regulate overall follicle activity inside the ovaries.

So, what we do is measure the amount of AMH in the blood and from this we can estimate the number of follicles there are in the ovaries. Once, we get an idea of how many follicles there are, the number of eggs can be estimated too.  Over the last 20 years, there's been a substantial body of medical literature about AMH and it's used in fertility clinics and doctors' practices around the world.

Patented Collection Technology

Previously, getting your AMH tested meant you had to travel to your local pathology centre with a referral, get a needle in your arm and have your blood drawn – yep, it’s a lot. But recent developments in microsampling technology mean that it can now be tested easily and accurately from home.

WHEN Fertility’s at-home test kit is powered by the Mitra sampling device, a patented collection technology that’s used by top institutions globally. From a simple fingerprick, you can collect your own sample and send it back to our partner laboratory using regular mail.

Importantly, your results are supported with a report built by fertility specialists so that you understand what they mean. If you receive
a low result then there’s an included tele-education appointment with one of our fertility nurses to answer any questions you might have.

Our at-home test kit is fully compliant with Australian Regulatory Bodies and our partner Melbourne laboratory carries internationally recognised NATA accreditation.

Australian Accredited Laboratory

Your samples are analysed using industry standard equipment to ensure clinical grade results.

All testing is performed in our Melbourne partner laboratory which is accredited to NATA's internationally recognised standards.

We’re fertility experts, and fellow humans.

Our Co-Chief Medical Advisors are leading Australian Fertility Specialists and provide the expert commentary on your report so you know what your result means (and what it doesn't). They also know that your result is about more than just a number, and lead our Nursing Team to make sure you feel supported every step of the way.

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Learn more about the science behind the Mitra IVD and our NATA approved Research Trial here.

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